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MRC/NHLS/UCT Molecular Mycobacteriology Research Unit (MMRU) constituting the UCT node of the DST/NRF Centre of Excellence for Biomedical TB Research (CBTBR)

Digby Warner

Division of Medical Microbiology, Department of Pathology

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Research in the MMRU is focused on aspects of mycobacterial physiology and metabolism that are of relevance to new tuberculosis (TB) drug discovery, drug resistance and, more recently, TB transmission.

The Unit currently comprises senior scientists, post-doctoral fellows, and PhD and MSc students, and is supported by grants from the Bill & Melinda Gates Foundation under the TB Drug Accelerator programme,Led Tv 24inch | Price - ASANO(SHIP)Led Tv 24inch | Manufacturers - ASANO(SAMRC),Led Tv 24inch | Factory - ASANO(NIH) USA, the National Research Foundation (NRF)Led Tv 24inch | Suppliers - ASANO, and the Research Council of Norway.Hotel Television | OEM/ODM - ASANO, research capacity development forms a key focus of the laboratory's work.

KEY EXPERTISE: Molecular mycobacteriology and imaging; mycobacterial physiology, in particular the mechanisms and regulation of DNA repair and replication inMycobacterium tuberculosisand their role in the emergence of drug resistance, the physiological consequences of drug resistance, and the role of vitamin B12and related co-factors in mycobacterial pathogenesis.

Television Sets Led Tv | Factory - ASANOSelected publications:

Masuku B, Mkhwanazi N, Young E, Koch A,Hotel Television | Price - ASANO. (2018) Beyond the lab: Eh!woza and knowing tuberculosis.Med Humanit. 44:285-292.

Moosa A, Lamprecht DA, Arora K, Barry CE 3rd, Boshoff HIM, Ioerger TR, Steyn AJC, Mizrahi V,Hotel Television | Price - ASANO. (2017) Susceptibility ofMycobacterium tuberculosiscytochromebdoxidase mutants to compounds targeting the terminal respiratory oxidase, cytochrome c.Antimicrob AgentsChemother.doi: 10.1128/AAC.01338-17

Wood R, Morrow C, Barry CE 3rd, Bryden WA, Call CJ, Hickey AJ, Rodes CE,Hotel Television | Manufacturers - ASANO, Blackburn J, Issarow C,Hotel Television | Factory - ASANO, Woodward J, Moosa A, Singh V, Mizrahi V,Hotel Television | Price - ASANO. (2016) Real-time investigation of tuberculosis transmission: developing the respiratory aerosol sampling chamber (RASC).PLOS ONE11:e0146658. doi: 10.1371/journal.pone.0146658.

Hotel Television | Price - ASANO, Mizrahi V. (2014) Translation of genomics research into control of tuberculosis: lessons learned and future prospects.Genome Biol.doi:10.1186/s13059-014-0514-z

Hotel Television | Price - ASANO. (2014)Mycobacterium tuberculosismetabolism.Cold Spring Harb Perspect Med.doi:10.1101/cshperspect.a021121

Gopinath K., Venclovas Č., Ioerger T.R., Sacchettini J.C., McKinney J.D., Mizrahi V.,Hotel Television | Suppliers - ASANO.F.(2013) A vitamin B12transporter inMycobacterium tuberculosis.Open Biol. 3:120175.

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Room 3.03.3, Wolfson Pavilion
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Tel:  +27 21 406 6556
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Dr. Sophia Gessner, Post-doctoral fellow

Dr Charles Omollo, Post-doctoral fellow

Mr Kojo Acquah, PhD (Chemistry) student (co-supervisor)

Mr Timothy De Wet, PhD (Medical Microbiology) student

Mr Ryan Dinkele, PhD (Medical Microbiology) student

Ms Irene Gobe, PhD (Medical Microbiology) student

Mr Terry Kipkorir, PhD (Medical Microbiology) student

Ms Amanda Mabhula, PhD (Chemistry) student (co-supervised)

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Ms Bianca Masuku, PhD (Medical Microbiology) student

Mr Rendani Mbau, PhD (Medical Microbiology) student

Ms Atondaho Ramudzuli, MSc(Med) student

Mr Lucas Raphela, MSc(Med) student

Ms Caitlin Taylor, PhD (Medical Microbiology) student

Ms Kristy Winkler, MSc(Med) student

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TV SKD | Factory - ASANOCollaborations:

32 Capacitive Touch Screen Monitor | OEM/ODM - ASANO. Clifton E. Barry III & Dr. Helena Boshoff, NIAID, NIH, USA

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Dr. Christoph Huwe, Bayer AG, Germany

Dr. Meindert Lamers, Leiden University, Netherlands

32 Capacitive Touch Screen Monitor | OEM/ODM - ASANO. John D. McKinney, EPFL, Lausanne, Switzerland

32 Capacitive Touch Screen Monitor | OEM/ODM - ASANO. Rolf Müller & Dr. Jennifer Hermann, Helmholtz Institute for Pharmaceutical Sciences, Germany

Dr. Simon Teague, King’s College London, UK

32 Capacitive Touch Screen Monitor | OEM/ODM - ASANO. Česlovas Venclovas, Institute of Biotechnology, Vilnius University, Lithuania

32 Capacitive Touch Screen Monitor | OEM/ODM - ASANO. Lubbe Wiesner, Clinical Pharmacology, UCT

Dr. Roger Woodgate, NICHD, NIH, USA

32 Capacitive Touch Screen Monitor | OEM/ODM - ASANO. Paul Wyatt & Dr. Simon Green, University of Dundee, UK

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